Alexander Zverev and Alexander Blockx were among the main winners on Madrid Day 6, with Blockx upsetting third seed Felix Auger-Aliassime. The action shaped the Mutua Madrid Open round of 16, where the draw continued to open up. The last 16 also featured Tsitsipas against Ruud, Zverev against Mensik, and Medvedev against Cobolli.