Rome second-round action will feature Daniil Medvedev against Tomas Machac and Andrey Rublev against Miomir Kecmanovic. Both Russians are set to make their tournament debuts in those matches. The schedule also includes Flavio Cobolli versus Terence Atmane and Felix Auger-Aliassime against Mariano Navone. Another listed first-round matchup has Tomas Machac meeting Stefanos Tsitsipas, with Denis Shapovalov facing Mariano Navone.