Match log updated: 2026-09-02 07:15 UTC
Matteo Berrettini — ATP Match Log
Main draw matches: 329 | W: 206 | L: 123 | Win %: 62.6%
| Opponent | Score | Result | H2H | Match Data | Date ↑ | Round | Tournament | Category | Surface |
|---|---|---|---|---|---|---|---|---|---|
| Fabio Fognini | 1-6 3-6 | L | H2H | Match data | May 16, 2017* | R64 | Italian Open | Masters 1000 | Clay |
| Franko Skugor | 6-1 3-6 2-6 | L | H2H | Match data | May 21, 2017* | Q1 | Geneva Open | ATP 250 | Clay |
| Marcelo Arevalo | 6-2 7-6(0) | W | H2H | Match data | Aug 28, 2017 | Q1 | US Open | Grand Slam | Hard |
| Stefanos Tsitsipas | 7-6(6) 6-7(4) 6-7(2) | L | H2H | Match data | Aug 29, 2017* | Q2 | US Open | Grand Slam | Hard |
| Liam Broady | 6-4 7-5 | W | H2H | Match data | Jan 1, 2018 | Q1 | Qatar Open | ATP 250 | Hard |
| Maximilian Marterer | 7-5 7-6(4) | W | H2H | Match data | Jan 1, 2018 | Q2 | Qatar Open | ATP 250 | Hard |
| Viktor Troicki | 4-6 7-6(5) 6-4 | W | H2H | Match data | Jan 3, 2018* | R32 | Qatar Open | ATP 250 | Hard |
| Peter Gojowczyk | 2-6 2-6 | L | H2H | Match data | Jan 4, 2018* | R16 | Qatar Open | ATP 250 | Hard |
| Liam Broady | 5-7 6-3 7-6(5) | W | H2H | Match data | Jan 15, 2018 | Q1 | Australian Open | Grand Slam | Hard |
| Hubert Hurkacz | 7-6(5) 6-3 | W | H2H | Match data | Jan 16, 2018* | Q2 | Australian Open | Grand Slam | Hard |
| Denis Kudla | 6-4 3-6 5-7 | L | H2H | Match data | Jan 16, 2018* | Q3 | Australian Open | Grand Slam | Hard |
| Adrian Mannarino | 4-6 4-6 4-6 | L | H2H | Match data | Jan 17, 2018* | R128 | Australian Open | Grand Slam | Hard |
| Marco Trungelliti | 3-6 6-3 3-6 | L | H2H | Match data | Feb 5, 2018 | Q1 | Montpellier Open | ATP 250 | Hard |
| Denis Kudla | 6-4 7-5 | W | H2H | Match data | Mar 8, 2018* | Q1 | Indian Wells Open | Masters 1000 | Hard |
| Peter Polansky | 3-6 6-1 3-6 | L | H2H | Match data | Mar 9, 2018* | Q2 | Indian Wells Open | Masters 1000 | Hard |
| Daniil Medvedev | 7-6(6) 5-7 4-6 | L | H2H | Match data | Mar 11, 2018* | R64 | Indian Wells Open | Masters 1000 | Hard |
| Filip Peliwo | 6-3 3-6 4-6 | L | H2H | Match data | Mar 21, 2018* | Q1 | Miami Open | Masters 1000 | Hard |
| Nikoloz Basilashvili | 6-7(2) 4-6 | L | H2H | Match data | Apr 12, 2018* | R32 | Grand Prix Hassan II | ATP 250 | Clay |
| Peter Nagy | 6-3 6-4 | W | H2H | Match data | Apr 23, 2018 | Q1 | Budapest | ATP 250 | Clay |
| Elias Ymer | 6-4 7-5 | W | H2H | Match data | Apr 23, 2018 | Q2 | Budapest | ATP 250 | Clay |
| Attila Balazs | 6-4 3-6 7-6(4) | W | H2H | Match data | Apr 26, 2018* | R32 | Budapest | ATP 250 | Clay |
| Aljaz Bedene | 6-7(2) 6-4 4-6 | L | H2H | Match data | Apr 27, 2018* | R16 | Budapest | ATP 250 | Clay |
| Taro Daniel | 5-7 3-6 | L | H2H | Match data | May 3, 2018* | R32 | Istanbul | ATP 250 | Clay |
| Mikhail Youzhny | 6-4 3-6 2-6 | L | H2H | Match data | May 6, 2018* | Q1 | Madrid Open | Masters 1000 | Clay |
| Frances Tiafoe | 6-3 7-6(1) | W | H2H | Match data | May 15, 2018* | R64 | Italian Open | Masters 1000 | Clay |
| Alexander Zverev | 5-7 2-6 | L | H2H | Match data | May 16, 2018* | R32 | Italian Open | Masters 1000 | Clay |
| Oscar Otte | 3-6 7-5 6-2 6-1 | W | H2H | Match data | May 29, 2018* | R128 | Roland Garros | Grand Slam | Clay |
| Ernests Gulbis | 6-2 3-6 6-4 6-3 | W | H2H | Match data | May 31, 2018* | R64 | Roland Garros | Grand Slam | Clay |
| Dominic Thiem | 3-6 7-6(5) 3-6 2-6 | L | H2H | Match data | Jun 2, 2018* | R32 | Roland Garros | Grand Slam | Clay |
| Dustin Brown | 6-7(5) 7-6(5) 7-6(4) | W | H2H | Match data | Jun 18, 2018 | Q1 | Halle Open | ATP 500 | Grass |
| Mikhail Youzhny | 3-6 6-7(7) | L | H2H | Match data | Jun 18, 2018 | Q2 | Halle Open | ATP 500 | Grass |
| Andreas Seppi | 3-6 5-7 | L | H2H | Match data | Jun 21, 2018* | R32 | Halle Open | ATP 500 | Grass |
| Andrea Basso | 6-3 6-3 | W | H2H | Match data | Jun 25, 2018 | Q1 | Eastbourne Open | ATP 250 | Grass |
| Carlos Gomez-Herrera | 6-2 7-6(3) | W | H2H | Match data | Jun 25, 2018 | Q2 | Eastbourne Open | ATP 250 | Grass |
| David Ferrer | 5-7 3-6 | L | H2H | Match data | Jun 27, 2018* | R32 | Eastbourne Open | ATP 250 | Grass |
| Jack Sock | 6-7(5) 6-7(3) 6-4 7-5 6-2 | W | H2H | Match data | Jul 4, 2018* | R128 | Wimbledon | Grand Slam | Grass |
| Gilles Simon | 3-6 6-7(4) 2-6 | L | H2H | Match data | Jul 5, 2018* | R64 | Wimbledon | Grand Slam | Grass |
| Leonardo Mayer | 3-6 6-3 6-4 | W | H2H | Match data | Jul 19, 2018* | R32 | Swedish Open | ATP 250 | Clay |
| Henri Laaksonen | 2-6 2-6 | L | H2H | Match data | Jul 20, 2018* | R16 | Swedish Open | ATP 250 | Clay |
| Radu Albot | 6-4 6-2 | W | H2H | Match data | Jul 26, 2018* | R32 | Swiss Open Gstaad | ATP 250 | Clay |
| Andrey Rublev | 6-3 6-3 | W | H2H | Match data | Jul 27, 2018* | R16 | Swiss Open Gstaad | ATP 250 | Clay |
| Feliciano Lopez | 6-4 6-3 | W | H2H | Match data | Jul 28, 2018* | QF | Swiss Open Gstaad | ATP 250 | Clay |
| Jurgen Zopp | 6-4 7-6(6) | W | H2H | Match data | Jul 28, 2018* | SF | Swiss Open Gstaad | ATP 250 | Clay |
| Roberto Bautista Agut | 7-6(9) 6-4 | W | H2H | Match data | Jul 29, 2018* | F | Swiss Open Gstaad | ATP 250 | Clay |
| Gilles Simon | 1-6 6-3 6-4 | W | H2H | Match data | Aug 1, 2018* | R32 | Austrian Open Kitzbühel | ATP 250 | Clay |
| Radu Albot | 6-3 6-7(3) 6-1 | W | H2H | Match data | Aug 2, 2018* | R16 | Austrian Open Kitzbühel | ATP 250 | Clay |
| Nicolas Jarry | 5-7 3-6 | L | H2H | Match data | Aug 3, 2018* | QF | Austrian Open Kitzbühel | ATP 250 | Clay |
| Julien Benneteau | 6-3 6-3 | W | H2H | Match data | Aug 21, 2018* | R64 | Winston-Salem Open | ATP 250 | Hard |
| Nikoloz Basilashvili | 7-5 6-3 | W | H2H | Match data | Aug 22, 2018* | R32 | Winston-Salem Open | ATP 250 | Hard |
| Hyeon Chung | 3-6 6-3 3-6 | L | H2H | Match data | Aug 23, 2018* | R16 | Winston-Salem Open | ATP 250 | Hard |
| Denis Kudla | 4-6 5-7 2-6 | L | H2H | Match data | Aug 29, 2018* | R128 | US Open | Grand Slam | Hard |
| Guillermo Garcia-Lopez | 7-6(5) 2-6 6-3 | W | H2H | Match data | Sep 20, 2018* | R32 | St. Petersburg | ATP 250 | Hard |
| Denis Shapovalov | 6-7(6) 6-4 0-6 | L | H2H | Match data | Sep 21, 2018* | R16 | St. Petersburg | ATP 250 | Hard |
| Prajnesh Gunneswaran | 6-3 6-4 | W | H2H | Match data | Sep 27, 2018* | R32 | Chengdu Open | ATP 250 | Hard |
| Matthew Ebden | 3-6 6-3 6-7(3) | L | H2H | Match data | Sep 28, 2018* | R16 | Chengdu Open | ATP 250 | Hard |
| Zhizhen Zhang | 6-3 6-2 | W | H2H | Match data | Oct 1, 2018 | Q1 | China Open | ATP 500 | Hard |
| Jiri Vesely | 6-3 6-2 | W | H2H | Match data | Oct 1, 2018 | Q2 | China Open | ATP 500 | Hard |
| Leonardo Mayer | 6-3 6-2 | W | H2H | Match data | Oct 4, 2018* | R32 | China Open | ATP 500 | Hard |
| Kyle Edmund | 5-7 7-6(2) 5-7 | L | H2H | Match data | Oct 5, 2018* | R16 | China Open | ATP 500 | Hard |
| Di Wu | 6-4 6-2 | W | H2H | Match data | Oct 7, 2018* | Q1 | Shanghai Masters | Masters 1000 | Hard |
| Mikhail Kukushkin | 5-7 4-6 | L | H2H | Match data | Oct 7, 2018* | Q2 | Shanghai Masters | Masters 1000 | Hard |
| Lukas Rosol | 3-6 6-4 4-6 | L | H2H | Match data | Oct 18, 2018* | R32 | Moscow | ATP 250 | Hard |
| Roberto Bautista Agut | 1-6 4-6 | L | H2H | Match data | Jan 2, 2019* | R32 | Qatar Open | ATP 250 | Hard |
| Mackenzie McDonald | 6-3 6-4 | W | H2H | Match data | Jan 9, 2019* | R32 | ASB Classic | ATP 250 | Hard |
| Leonardo Mayer | 7-5 6-7(5) 3-6 | L | H2H | Match data | Jan 10, 2019* | R16 | ASB Classic | ATP 250 | Hard |
| Stefanos Tsitsipas | 7-6(3) 4-6 3-6 6-7(4) | L | H2H | Match data | Jan 16, 2019* | R128 | Australian Open | Grand Slam | Hard |
| Denis Istomin | 6-4 7-6(7) | W | H2H | Match data | Feb 7, 2019* | R32 | Sofia | ATP 250 | Hard |
| Karen Khachanov | 6-7(6) 6-3 6-4 | W | H2H | Match data | Feb 8, 2019* | R16 | Sofia | ATP 250 | Hard |
| Fernando Verdasco | 4-6 7-5 6-4 | W | H2H | Match data | Feb 9, 2019* | QF | Sofia | ATP 250 | Hard |
| Marton Fucsovics | 7-5 5-7 3-6 | L | H2H | Match data | Feb 9, 2019* | SF | Sofia | ATP 250 | Hard |
| Jeremy Chardy | 7-6(12) 7-6(0) | W | H2H | Match data | Feb 21, 2019* | R32 | Marseille | ATP 250 | Hard |
| Andrey Rublev | 3-6 6-7(2) | L | H2H | Match data | Feb 22, 2019* | R16 | Marseille | ATP 250 | Hard |
| Denis Kudla | 6-2 5-7 5-7 | L | H2H | Match data | Feb 27, 2019* | R32 | Dubai Tennis Championships | ATP 500 | Hard |
| Sam Querrey | 6-7(5) 6-2 4-6 | L | H2H | Match data | Mar 9, 2019* | R128 | Indian Wells Open | Masters 1000 | Hard |
| Hubert Hurkacz | 4-6 3-6 | L | H2H | Match data | Mar 22, 2019* | R128 | Miami Open | Masters 1000 | Hard |
| Grigor Dimitrov | 5-7 4-6 | L | H2H | Match data | Apr 16, 2019* | R64 | Monte-Carlo Masters | Masters 1000 | Clay |
| Mikhail Kukushkin | 6-4 6-4 | W | H2H | Match data | Apr 25, 2019* | R32 | Budapest | ATP 250 | Clay |
| Aljaz Bedene | 7-6(8) 6-2 | W | H2H | Match data | Apr 26, 2019* | R16 | Budapest | ATP 250 | Clay |
| Pablo Cuevas | 6-3 1-6 6-3 | W | H2H | Match data | Apr 27, 2019* | QF | Budapest | ATP 250 | Clay |
| Laslo Djere | 6-4 6-2 | W | H2H | Match data | Apr 27, 2019* | SF | Budapest | ATP 250 | Clay |
| Filip Krajinovic | 4-6 6-3 6-1 | W | H2H | Match data | Apr 28, 2019* | F | Budapest | ATP 250 | Clay |
| Denis Istomin | 7-6(5) 6-3 | W | H2H | Match data | May 2, 2019* | R32 | Munich Open | ATP 250 | Clay |
| Denis Kudla | 7-5 6-3 | W | H2H | Match data | May 3, 2019* | R16 | Munich Open | ATP 250 | Clay |
| Philipp Kohlschreiber | 4-6 7-5 6-4 | W | H2H | Match data | May 4, 2019* | QF | Munich Open | ATP 250 | Clay |
| Roberto Bautista Agut | 6-4 6-2 | W | H2H | Match data | May 4, 2019* | SF | Munich Open | ATP 250 | Clay |
| Cristian Garin | 1-6 6-3 6-7(1) | L | H2H | Match data | May 5, 2019* | F | Munich Open | ATP 250 | Clay |
| Lucas Pouille | 6-2 6-4 | W | H2H | Match data | May 14, 2019* | R64 | Italian Open | Masters 1000 | Clay |
| Alexander Zverev | 7-5 7-5 | W | H2H | Match data | May 15, 2019* | R32 | Italian Open | Masters 1000 | Clay |
| Diego Schwartzman | 3-6 4-6 | L | H2H | Match data | May 17, 2019* | R16 | Italian Open | Masters 1000 | Clay |
| Pablo Andujar | 6-7(3) 6-4 6-4 6-2 | W | H2H | Match data | May 28, 2019* | R128 | Roland Garros | Grand Slam | Clay |
| Casper Ruud | 4-6 5-7 3-6 | L | H2H | Match data | May 30, 2019* | R64 | Roland Garros | Grand Slam | Clay |
| Nick Kyrgios | 6-3 6-4 | W | H2H | Match data | Jun 13, 2019* | R32 | Stuttgart Open | ATP 250 | Grass |
| Karen Khachanov | 6-4 6-2 | W | H2H | Match data | Jun 14, 2019* | R16 | Stuttgart Open | ATP 250 | Grass |
| Denis Kudla | 6-3 6-3 | W | H2H | Match data | Jun 15, 2019* | QF | Stuttgart Open | ATP 250 | Grass |
| Jan-Lennard Struff | 6-4 7-5 | W | H2H | Match data | Jun 15, 2019* | SF | Stuttgart Open | ATP 250 | Grass |
| Felix Auger-Aliassime | 6-4 7-6(11) | W | H2H | Match data | Jun 16, 2019* | F | Stuttgart Open | ATP 250 | Grass |
| Nikoloz Basilashvili | 6-4 6-4 | W | H2H | Match data | Jun 20, 2019* | R32 | Halle Open | ATP 500 | Grass |
| Andreas Seppi | 4-6 6-3 6-2 | W | H2H | Match data | Jun 21, 2019* | R16 | Halle Open | ATP 500 | Grass |
| Karen Khachanov | 6-2 7-6(4) | W | H2H | Match data | Jun 22, 2019* | QF | Halle Open | ATP 500 | Grass |
| David Goffin | 6-7(4) 3-6 | L | H2H | Match data | Jun 22, 2019* | SF | Halle Open | ATP 500 | Grass |
| Aljaz Bedene | 3-6 6-3 6-2 7-6(3) | W | H2H | Match data | Jul 3, 2019* | R128 | Wimbledon | Grand Slam | Grass |
| Marcos Baghdatis | 6-1 7-6(4) 6-3 | W | H2H | Match data | Jul 4, 2019* | R64 | Wimbledon | Grand Slam | Grass |
| Diego Schwartzman | 6-7(5) 7-6(2) 4-6 7-6(5) 6-3 | W | H2H | Match data | Jul 7, 2019* | R32 | Wimbledon | Grand Slam | Grass |
| Roger Federer | 1-6 2-6 2-6 | L | H2H | Match data | Jul 9, 2019* | R16 | Wimbledon | Grand Slam | Grass |
| Juan Ignacio Londero | 6-7(3) 3-6 | L | H2H | Match data | Aug 13, 2019* | R64 | Cincinnati Open | Masters 1000 | Hard |
| Richard Gasquet | 6-4 6-3 2-6 6-2 | W | H2H | Match data | Aug 28, 2019* | R128 | US Open | Grand Slam | Hard |
| Jordan Thompson | 7-5 7-6(5) 4-6 6-1 | W | H2H | Match data | Aug 29, 2019* | R64 | US Open | Grand Slam | Hard |
| Alexei Popyrin | 6-4 6-4 6-7(3) 7-6(2) | W | H2H | Match data | Sep 1, 2019* | R32 | US Open | Grand Slam | Hard |
| Andrey Rublev | 6-1 6-4 7-6(6) | W | H2H | Match data | Sep 3, 2019* | R16 | US Open | Grand Slam | Hard |
| Gael Monfils | 3-6 6-3 6-2 3-6 7-6(5) | W | H2H | Match data | Sep 5, 2019* | QF | US Open | Grand Slam | Hard |
| Rafael Nadal | 6-7(6) 4-6 1-6 | L | H2H | Match data | Sep 7, 2019* | SF | US Open | Grand Slam | Hard |
| Roberto Carballes Baena | 6-1 6-2 | W | H2H | Match data | Sep 20, 2019* | R16 | St. Petersburg | ATP 250 | Hard |
| Egor Gerasimov | 6-7(5) 6-7(3) | L | H2H | Match data | Sep 21, 2019* | QF | St. Petersburg | ATP 250 | Hard |
| Andy Murray | 6-7(2) 6-7(7) | L | H2H | Match data | Oct 3, 2019* | R32 | China Open | ATP 500 | Hard |
| Jan-Lennard Struff | 6-2 6-1 | W | H2H | Match data | Oct 8, 2019* | R64 | Shanghai Masters | Masters 1000 | Hard |
| Cristian Garin | 6-3 6-3 | W | H2H | Match data | Oct 9, 2019* | R32 | Shanghai Masters | Masters 1000 | Hard |
| Roberto Bautista Agut | 7-6(5) 6-4 | W | H2H | Match data | Oct 11, 2019* | R16 | Shanghai Masters | Masters 1000 | Hard |
| Dominic Thiem | 7-6(8) 6-4 | W | H2H | Match data | Oct 12, 2019* | QF | Shanghai Masters | Masters 1000 | Hard |
| Alexander Zverev | 3-6 4-6 | L | H2H | Match data | Oct 12, 2019* | SF | Shanghai Masters | Masters 1000 | Hard |
| Kyle Edmund | 3-6 6-3 6-4 | W | H2H | Match data | Oct 24, 2019* | R32 | Vienna Open | ATP 500 | Hard |
| Grigor Dimitrov | 7-6(5) 7-6(1) | W | H2H | Match data | Oct 25, 2019* | R16 | Vienna Open | ATP 500 | Hard |
| Andrey Rublev | 7-5 7-6(4) | W | H2H | Match data | Oct 26, 2019* | QF | Vienna Open | ATP 500 | Hard |
| Dominic Thiem | 6-3 5-7 3-6 | L | H2H | Match data | Oct 26, 2019* | SF | Vienna Open | ATP 500 | Hard |
| Jo-Wilfried Tsonga | 4-6 3-6 | L | H2H | Match data | Oct 31, 2019* | R32 | Paris Masters | Masters 1000 | Hard |
| Dominic Thiem | 7-6(3) 6-3 | W | H2H | Match data | Nov 11, 2019 | RR | ATP Finals | ATP Finals | Hard |
| Novak Djokovic | 2-6 1-6 | L | H2H | Match data | Nov 11, 2019 | RR | ATP Finals | ATP Finals | Hard |
| Roger Federer | 6-7(2) 3-6 | L | H2H | Match data | Nov 11, 2019 | RR | ATP Finals | ATP Finals | Hard |
| Andrew Harris | 6-3 6-1 6-3 | W | H2H | Match data | Jan 22, 2020* | R128 | Australian Open | Grand Slam | Hard |
| Tennys Sandgren | 6-7(7) 4-6 6-4 6-2 5-7 | L | H2H | Match data | Jan 24, 2020* | R64 | Australian Open | Grand Slam | Hard |
| Emil Ruusuvuori | 6-4 6-7(3) 7-5 | W | H2H | Match data | Aug 25, 2020* | R32 | Cincinnati Open | Masters 1000 | Hard |
| Reilly Opelka | 3-6 6-7(4) | L | H2H | Match data | Aug 27, 2020* | R16 | Cincinnati Open | Masters 1000 | Hard |
| Go Soeda | 7-6(5) 6-1 6-4 | W | H2H | Match data | Sep 2, 2020* | R128 | US Open | Grand Slam | Hard |
| Ugo Humbert | 6-4 6-4 7-6(6) | W | H2H | Match data | Sep 3, 2020* | R64 | US Open | Grand Slam | Hard |
| Casper Ruud | 6-4 6-4 6-2 | W | H2H | Match data | Sep 6, 2020* | R32 | US Open | Grand Slam | Hard |
| Andrey Rublev | 6-4 3-6 3-6 3-6 | L | H2H | Match data | Sep 8, 2020* | R16 | US Open | Grand Slam | Hard |
| Federico Coria | 7-5 6-1 | W | H2H | Match data | Sep 17, 2020* | R32 | Italian Open | Masters 1000 | Clay |
| Stefano Travaglia | 7-6(5) 7-6(1) | W | H2H | Match data | Sep 19, 2020* | R16 | Italian Open | Masters 1000 | Clay |
| Casper Ruud | 6-4 3-6 6-7(5) | L | H2H | Match data | Sep 20, 2020* | QF | Italian Open | Masters 1000 | Clay |
| Vasek Pospisil | 6-3 6-1 6-3 | W | H2H | Match data | Sep 29, 2020* | R128 | Roland Garros | Grand Slam | Clay |
| Lloyd Harris | 6-4 4-6 6-2 6-3 | W | H2H | Match data | Oct 1, 2020* | R64 | Roland Garros | Grand Slam | Clay |
| Daniel Altmaier | 2-6 6-7(5) 4-6 | L | H2H | Match data | Oct 3, 2020* | R32 | Roland Garros | Grand Slam | Clay |
| Marcos Giron | 6-7(3) 7-6(0) 5-7 | L | H2H | Match data | Nov 5, 2020* | R32 | Paris Masters | Masters 1000 | Hard |
| Ergi Kirkin | 6-0 6-4 | W | H2H | Match data | Jan 8, 2021* | R32 | Antalya | ATP 250 | Hard |
| Dimitar Kuzmanov | 6-2 6-3 | W | H2H | Match data | Jan 9, 2021* | R16 | Antalya | ATP 250 | Hard |
| Alexander Bublik | 6-7(6) 4-6 | L | H2H | Match data | Jan 10, 2021* | QF | Antalya | ATP 250 | Hard |
| Kevin Anderson | 7-6(9) 7-5 6-3 | W | H2H | Match data | Feb 10, 2021* | R128 | Australian Open | Grand Slam | Hard |
| Tomas Machac | 6-3 6-2 4-6 6-3 | W | H2H | Match data | Feb 11, 2021* | R64 | Australian Open | Grand Slam | Hard |
| Karen Khachanov | 7-6(1) 7-6(5) 7-6(5) | W | H2H | Match data | Feb 14, 2021* | R32 | Australian Open | Grand Slam | Hard |
| Stefanos Tsitsipas | (w/o) | L | H2H | Match data | Feb 16, 2021* | R16 | Australian Open | Grand Slam | Hard |
| Alejandro Davidovich Fokina | 5-7 3-6 | L | H2H | Match data | Apr 14, 2021* | R32 | Monte-Carlo Masters | Masters 1000 | Clay |
| Marco Cecchinato | 6-4 6-3 | W | H2H | Match data | Apr 23, 2021* | R16 | Belgrade | ATP 250 | Clay |
| Filip Krajinovic | 6-4 6-4 | W | H2H | Match data | Apr 24, 2021* | QF | Belgrade | ATP 250 | Clay |
| Taro Daniel | 6-1 6-7(5) 6-0 | W | H2H | Match data | Apr 24, 2021* | SF | Belgrade | ATP 250 | Clay |
| Aslan Karatsev | 6-1 3-6 7-6(0) | W | H2H | Match data | Apr 25, 2021* | F | Belgrade | ATP 250 | Clay |
| Fabio Fognini | 6-3 6-4 | W | H2H | Match data | May 5, 2021* | R32 | Madrid Open | Masters 1000 | Clay |
| Federico Delbonis | 7-6(4) 6-4 | W | H2H | Match data | May 7, 2021* | R16 | Madrid Open | Masters 1000 | Clay |
| Cristian Garin | 5-7 6-3 6-0 | W | H2H | Match data | May 8, 2021* | QF | Madrid Open | Masters 1000 | Clay |
| Casper Ruud | 6-4 6-4 | W | H2H | Match data | May 8, 2021* | SF | Madrid Open | Masters 1000 | Clay |
| Alexander Zverev | 7-6(8) 4-6 3-6 | L | H2H | Match data | May 9, 2021* | F | Madrid Open | Masters 1000 | Clay |
| Nikoloz Basilashvili | 4-6 6-2 6-4 | W | H2H | Match data | May 11, 2021* | R64 | Italian Open | Masters 1000 | Clay |
| John Millman | 6-4 6-2 | W | H2H | Match data | May 12, 2021* | R32 | Italian Open | Masters 1000 | Clay |
| Stefanos Tsitsipas | 6-7(3) 2-6 | L | H2H | Match data | May 14, 2021* | R16 | Italian Open | Masters 1000 | Clay |
| Taro Daniel | 6-0 6-4 4-6 6-4 | W | H2H | Match data | Jun 1, 2021* | R128 | Roland Garros | Grand Slam | Clay |
| Federico Coria | 6-3 6-3 6-2 | W | H2H | Match data | Jun 3, 2021* | R64 | Roland Garros | Grand Slam | Clay |
| Soonwoo Kwon | 7-6(6) 6-3 6-4 | W | H2H | Match data | Jun 5, 2021* | R32 | Roland Garros | Grand Slam | Clay |
| Roger Federer | (w/o) | W | H2H | Match data | Jun 8, 2021* | R16 | Roland Garros | Grand Slam | Clay |
| Novak Djokovic | 3-6 2-6 7-6(5) 5-7 | L | H2H | Match data | Jun 10, 2021* | QF | Roland Garros | Grand Slam | Clay |
| Stefano Travaglia | 7-6(5) 7-6(4) | W | H2H | Match data | Jun 17, 2021* | R32 | Queen's Club Championships | ATP 500 | Grass |
| Andy Murray | 6-3 6-3 | W | H2H | Match data | Jun 18, 2021* | R16 | Queen's Club Championships | ATP 500 | Grass |
| Daniel Evans | 7-6(5) 6-3 | W | H2H | Match data | Jun 19, 2021* | QF | Queen's Club Championships | ATP 500 | Grass |
| Alex de Minaur | 6-4 6-4 | W | H2H | Match data | Jun 19, 2021* | SF | Queen's Club Championships | ATP 500 | Grass |
| Cameron Norrie | 6-4 6-7(5) 6-3 | W | H2H | Match data | Jun 20, 2021* | F | Queen's Club Championships | ATP 500 | Grass |
| Guido Pella | 6-4 3-6 6-4 6-0 | W | H2H | Match data | Jun 30, 2021* | R128 | Wimbledon | Grand Slam | Grass |
| Botic van de Zandschulp | 6-3 6-4 7-6(4) | W | H2H | Match data | Jul 1, 2021* | R64 | Wimbledon | Grand Slam | Grass |
| Aljaz Bedene | 6-4 6-4 6-4 | W | H2H | Match data | Jul 4, 2021* | R32 | Wimbledon | Grand Slam | Grass |
| Ilya Ivashka | 6-4 6-3 6-1 | W | H2H | Match data | Jul 6, 2021* | R16 | Wimbledon | Grand Slam | Grass |
| Felix Auger-Aliassime | 6-3 5-7 7-5 6-3 | W | H2H | Match data | Jul 8, 2021* | QF | Wimbledon | Grand Slam | Grass |
| Hubert Hurkacz | 6-3 6-0 6-7(3) 6-4 | W | H2H | Match data | Jul 10, 2021* | SF | Wimbledon | Grand Slam | Grass |
| Novak Djokovic | 7-6(4) 4-6 4-6 3-6 | L | H2H | Match data | Jul 11, 2021* | F | Wimbledon | Grand Slam | Grass |
| Albert Ramos-Vinolas | 6-7(5) 6-3 7-5 | W | H2H | Match data | Aug 18, 2021* | R32 | Cincinnati Open | Masters 1000 | Hard |
| Felix Auger-Aliassime | 4-6 3-6 | L | H2H | Match data | Aug 20, 2021* | R16 | Cincinnati Open | Masters 1000 | Hard |
| Jeremy Chardy | 7-6(5) 7-6(7) 6-3 | W | H2H | Match data | Sep 1, 2021* | R128 | US Open | Grand Slam | Hard |
| Corentin Moutet | 7-6(2) 4-6 6-4 6-3 | W | H2H | Match data | Sep 2, 2021* | R64 | US Open | Grand Slam | Hard |
| Ilya Ivashka | 6-7(5) 6-2 6-4 2-6 6-3 | W | H2H | Match data | Sep 5, 2021* | R32 | US Open | Grand Slam | Hard |
| Oscar Otte | 6-4 3-6 6-3 6-2 | W | H2H | Match data | Sep 7, 2021* | R16 | US Open | Grand Slam | Hard |
| Novak Djokovic | 7-5 2-6 2-6 3-6 | L | H2H | Match data | Sep 9, 2021* | QF | US Open | Grand Slam | Hard |
| Alejandro Tabilo | 6-4 7-5 | W | H2H | Match data | Oct 10, 2021* | R64 | Indian Wells Open | Masters 1000 | Hard |
| Taylor Fritz | 4-6 3-6 | L | H2H | Match data | Oct 12, 2021* | R32 | Indian Wells Open | Masters 1000 | Hard |
| Alexei Popyrin | 7-6(3) 6-3 | W | H2H | Match data | Oct 28, 2021* | R32 | Vienna Open | ATP 500 | Hard |
| Nikoloz Basilashvili | 6-7(5) 6-2 6-3 | W | H2H | Match data | Oct 29, 2021* | R16 | Vienna Open | ATP 500 | Hard |
| Carlos Alcaraz | 1-6 7-6(2) 6-7(5) | L | H2H | Match data | Oct 30, 2021* | QF | Vienna Open | ATP 500 | Hard |
| Alexander Zverev | 6-7(7) 0-1 (ret.) | L | H2H | Match data | Nov 15, 2021 | RR | ATP Finals | ATP Finals | Hard |
| Brandon Nakashima | 4-6 6-2 7-6(5) 6-3 | W | H2H | Match data | Jan 19, 2022* | R128 | Australian Open | Grand Slam | Hard |
| Stefan Kozlov | 6-1 4-6 6-4 6-1 | W | H2H | Match data | Jan 20, 2022* | R64 | Australian Open | Grand Slam | Hard |
| Carlos Alcaraz | 6-2 7-6(3) 4-6 2-6 7-6(5) | W | H2H | Match data | Jan 23, 2022* | R32 | Australian Open | Grand Slam | Hard |
| Pablo Carreno Busta | 7-5 7-6(4) 6-4 | W | H2H | Match data | Jan 25, 2022* | R16 | Australian Open | Grand Slam | Hard |
| Gael Monfils | 6-4 6-4 3-6 3-6 6-2 | W | H2H | Match data | Jan 27, 2022* | QF | Australian Open | Grand Slam | Hard |
| Rafael Nadal | 3-6 2-6 6-3 3-6 | L | H2H | Match data | Jan 29, 2022* | SF | Australian Open | Grand Slam | Hard |
| Thiago Monteiro | 6-4 6-7(6) 6-3 | W | H2H | Match data | Feb 18, 2022* | R16 | Rio Open | ATP 500 | Clay |
| Carlos Alcaraz | 2-6 6-2 2-6 | L | H2H | Match data | Feb 19, 2022* | QF | Rio Open | ATP 500 | Clay |
1 scheduled match shown in the table; scheduled matches are not included in the record above. 23 qualifying matches shown in the table; qualifying is excluded from main-draw summaries and leaderboards. Estimated from the tournament schedule where an exact match date is unavailable. Arrows show an edition's recorded category and documented modern equivalent; unresolved editions keep their recorded category. Mapping details.